Senior Bioinformatics Scientist in Cancer Genomics

Senior Bioinformatics Scientist in Cancer Genomics

We are seeking a senior level bioinformatician with experience in NGS data analysis and cancer genomics to join our bioinformatics team. In this role, you will work with a team of talented experts to further develop our state-of-the-art computational platform, NeoSELECT, for detection of cancer signatures that can give clinical response in patients. Your primary focus will be on analysis and interpretation of high-throughput genomic and other molecular data. You may also design and perform simulation studies for various evaluation purposes.

You will:
  • Work with our internal team and external bioinformatics collaborators on further development of NeoSELECT platform for neoepitope prediction
  • Apply existing and develop novel approaches to conduct analyses of genomics data from Vaccibody's clinical trials in close collaboration with immunologists, oncologists and other bioinformaticians. Current projects include genomic and transcriptomic analyses of solid tumors and liquid biopsies.
  • Contribute to agile development and documentation of the NeoSELECT platform
Your Qualifications:
  • PhD/MSc in bioinformatics, biostatistics, computational biology or relevant discipline
  • Applied experience in analysis of NGS sequencing data and running/developing variant discovery pipelines
  • Extensive experience in programming, and experience in languages often used in bioinformatics, statistical data analysis and machine learning (e.g., R/Python)
  • Proficiency in Linux/cloud/HPC environment, version control tools, and reproducible research practices
  • Demonstrated ability to uncover new biological insights from large genomics datasets
  • Experience from variant phasing and variant detection involving frameshifts, fusions, microsatellites is a major plus
  • Preferably, experience with machine learning techniques/predictive modeling
  • Preferably, experience working with TCGA, COSMIC, 1000 Genomes, ENCODE, or GTEx data
Your personal attributes
  • Innovative - enjoy developing new insights and pursuing improvements
  • Responsible - take ownership and deliver on commitments
  • Team oriented with good written and verbal communication skills
If you perfer to send you resume and cover letter via email, please send to msekelja @ vaccibody.com
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Om arbetsgivaren

Vaccibody is a clinical stage immune-oncology company whose mission is to treat and prevent cancer, as well as pre-cancerous and infectious diseases. Through its innovative design Vaccibody's proprietary vaccine platform generates rapid, durable and broad antibody and T cell responses leading to remarkably potent vaccines. Vaccibody has developed compelling preclinical data and initiated the first clinical trial with VB10.16, a therapeutic vaccine against cervical precancerous lesion. Also, Vaccibody has an on-going clinical trial with neoantigen-based individualized cancer vaccines and is using the Vaccibody technology together with the power of next-generation sequencing and state-of-the-art computer science to generate first-in-class therapeutics to treat cancers with a high unmet medical need. This would not be possible without Vaccibody's exceptionally talented people working in a genuinely positive environment.