Specialist/ Senior Scientist Cell Line Development

Specialist/ Senior Scientist Cell Line Development

At BioInvent we are experts on antibodies and cancer immunology. We strive to develop first-in-class immuno- modulatory antibody-based - treatments that have significant potential to improve cancer outcome and cancer patients' quality of life. We are based in Lund in Sweden and amongst our 70+ employees cover all parts for drug development including preclinical research, manufacturing and clinical trials. Together we are creating an exciting future of BioInvent and we welcome you to be part of this journey as one of our Specialist/ Senior Scientist Cell Line Development

We are seeking a Specialist/ Senior Scientist with hands-on experience in establishing high producing mammalian cell lines for cGMP manufacture of monoclonal antibodies. This position sits in Process
Development group which is placed in the Division of Technical Operations responsible for all CMC related activities including process development, manufacturing, QC and QA. We generate cell lines, develop processes and supply BioInvent's clinical projects with antibodies, and additionally serve external customers as a CMO. At BioInvent we mainly use CHO cells for production and cultivate cells in single use bioreactors in sizes up to
1000L.

Key Responsibilities
  • Design and execute cell line development activities
  • Generate regulatory compliant clonal stable cell lines with desirable quality attributes
  • Support upstream process development through design and execution of cell culture experiments
  • Share your expertise and be able to train and develop other team members
  • Interaction with customer
  • Draft and revise documents such as SOPs, methods and technical reports
  • Support preparing regulatory submissions
  • Identify, recommend and implement improvements related to routine functions
  • Strategic technology development
  • Be subject matter expert during audit
  • Requirements
  • Experience and Qualifications
  • Minimum 3 years experience of cell line development for cGMP manufacture of biologics
  • Expertise in cell line development, including vector construction, stable transfection, Pool and clone generation, clone evaluation and selection, cell age stability studies and research cell bank establishment
  • Experience in routine maintenance and analysis of suspension CHO cells
  • Documented ability to work across multiple projects in parallel
  • Experience in customer relations and project planning
  • Fluent in written and spoken English and understand Swedish

In addition, experience from vector engineering will be an advantage as we currently are working with novel technologies to optimize our vectors and expand our expression platform.

Skills and Capabilities
We are looking for a driven, structured, self-motivated and responsible person, who easily collaborates and communicates with others both verbally and in writing. You have excellent problem-solving skills and you enjoy creating efficient working methods and contributing with your experience to ensure continuous improvements.

Your attitude and personality are of great importance - you are thorough yet efficient and strongly committed to making things happen. You understand the importance of achieving results, being flexible and adjusting to our processes, keeping deadlines and securing the highest quality of your work. You are enthusiastic and enjoy generating results and achieving goals both individually and jointly with your team.
If you match above described profile and are excited to contribute to BioInvent's important cancer research journey, we welcome you to apply for this position.

Other information
The position is a full-time position based in Lund, Sweden. The working hours are mainly day-time, but the service will to some extent also be associated with certain on-call work during weekends or evenings. You will report to Team Leader Process development & Manufacturing Support.

Application
Please send your application (CV and personal letter) through our website https://careers.bioinvent.com/

Selection is on-going and interviews will be held continuously which means the positions can be filled before deadline. Please make sure to send in your application as soon as possible, at the latest 2020-01-04

BioInvent has a collective agreement and contact persons for the Unions are: Fredrik Wiberg, Akademikerföreningen and Jenny Nilsson, Unionenklubben
Mer info
Område Lund
Yrkesroll Organisation & ledning, Hälsa & Sjukvård, Medicinsk forskning & Laboratorieverksamhet
Typ av anställning Heltid, Tillsvidareanställd
Hemsida http://bioinvent.com
Sista ansökningsdag 4 jan 2021 (35 dagar kvar)

Om arbetsgivaren

BioInvent International AB (OMXS: BINV) is a clinical stage company that discovers and develops novel and first-in-class immuno- modulatory antibodies for cancer therapies, with two ongoing programs in Phase l/ll clinical trials for the treatment of hematological cancer and solid tumors, respectively. Two preclinical programs in solid tumors are expected to have entered clinical trials by the end of
2020.

The Company's validated, proprietary F.I.R.S.T™ technology platform simultaneously identifies both targets and the antibodies that bind to them, generating many promising new drug candidates to fuel the Company's own clinical development pipeline or for additional licensing and partnering. The Company generates revenues from research collaborations and license agreements with multiple top-tier pharmaceutical companies, as well as from producing antibodies for third parties in the Company's fully integrated manufacturing unit.

More information is available at www.bioinvent.com